Dioxybenzone

CAT: 0804-HY-B0966-01Size: 500 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0966-01Size:500 mg
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Description
Dioxybenzone (Benzophenone-8; UV-24) is an organic compound used to block UVB and short-wave UVA (ultraviolet) radiation. Dioxybenzone has orally activity. Dioxybenzone exhibits estrogenic disrupting effect. Dioxybenzone up-regulates inflammatory cytokines. Dioxybenzone can be used for cancer, reproductive system disease and inflammatory disease study[1][2][3].
CAS Number
[131-53-3]
Product Name Alternative
Benzophenone-8; UV-24
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Dioxybenzone.html
Concentration
10mM
Purity
99.57
Solubility
DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL
Smiles
O=C(C1=CC=C(OC)C=C1O)C2=CC=CC=C2O
Molecular Formula
C14H12O4
Molecular Weight
244.24
Precautions
H315, H319, H335
References & Citations
[1]Rao GS, et al. Oral chemoprevention of skin cancer in mice by benzophenone sunscreens dioxybenzone and octabenzone in drinking water. Anticancer Res. 2013 Jun;33 (6) :2535-40.|[2]Zhan T, et al. Transcriptome aberration in mice uterus associated with steroid hormone response and inflammation induced by dioxybenzone and its metabolites. Environ Pollut. 2021 Oct 1;286:117294.|[3]Sherwood VF, et al. Altered UV absorbance and cytotoxicity of chlorinated sunscreen agents. Cutan Ocul Toxicol. 2012 Dec;31 (4) :273-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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