Oxacillin-d5

• Description :

  Oxacillin-d5 is the deuterium labeled Oxacillin[1]. Oxacillin is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens[2].

• UNSPSC :

  12352005

• Target :

  Antibiotic; Bacterial

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Solubility :

  10 mM in DMSO

• Smiles :

  OC([C@@H]1N2[C@@](SC1(C)C)([H])[C@@H](C2=O)NC(C3=C(C)ON=C3C4=C([2H])C([2H])=C([2H])C([2H])=C4[2H])=O)=O

• Molecular Formula :

  C19H14D5N3O5S

• Molecular Weight :

  406.47

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]KIRBY WM, et al. Oxacillin: laboratory and clinical evaluation. JAMA. 1962 Sep 1;181:739-44.|[3]Yurchenco JA, et al. Nafcillin and oxacillin: comparative antistaphylococcal activity in mice. J Antibiot (Tokyo) . 1976 Apr29 (4) :460-5.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported