Oxacillin-d5

• Description:

  Oxacillin-d5 is the deuterium labeled Oxacillin[1]. Oxacillin is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens[2].

• UNSPSC:

  12352005

• Target:

  Antibiotic; Bacterial

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Solubility:

  10 mM in DMSO

• Smiles:

  OC ([C@@H]1N2[C@@] (SC1 (C) C) ([H]) [C@@H] (C2=O) NC (C3=C (C) ON=C3C4=C ([2H]) C ([2H]) =C ([2H]) C ([2H]) =C4[2H]) =O) =O

• Molecular Formula:

  C19H14D5N3O5S

• Molecular Weight:

  406.47

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]KIRBY WM, et al. Oxacillin: laboratory and clinical evaluation. JAMA. 1962 Sep 1;181:739-44.|[3]Yurchenco JA, et al. Nafcillin and oxacillin: comparative antistaphylococcal activity in mice. J Antibiot (Tokyo) . 1976 Apr29 (4) :460-5.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported