Oxacillin

• Description :

  Oxacillin is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens[1].

• CAS Number :

  [66-79-5]

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H312-H332

• Target :

  Antibiotic; Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/oxacillin.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(C3=C(C)ON=C3C4=CC=CC=C4)=O)N1C2=O)O

• Molecular Formula :

  C19H19N3O5S

• Molecular Weight :

  401.44

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

• References & Citations :

  [1]KIRBY WM, et al. Oxacillin: laboratory and clinical evaluation. JAMA. 1962 Sep 1;181:739-44.|[2]Yurchenco JA, et al. Nafcillin and oxacillin: comparative antistaphylococcal activity in mice. J Antibiot (Tokyo) . 1976 Apr;29 (4) :460-5.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• Isoform :

  β-lactam

• Citation 01 :

  Curr Microbiol. 2023 May 31;80 (7) :230.|Microorganisms. 2024 Jan 25;12 (2) :256.|ACS Omega. 2022 Mar 3;7 (10) :9004-9014.|AMB Express. 2024 Dec 24;14 (1) :141.|bioRxiv. 2024 May 10.|bioRxiv. 2025 Oct 27.|BMC Microbiol. 2023 Apr 20;23 (1) :109.|Emerg Microbes Infect. 2024 Dec;13 (1) :2321981.|iScience. 2022 Jan 5;25 (2) :103731.|Microbiol Spectr. 2022 Apr 27;10 (2) :e0054121.|Research Square Print. December 5th, 2022.|Biomed Res Int. 2018 Jul 2:2018:3579832.|Front Microbiol. 2020 Jul 31:11:1720.