Glyphosate-d2-1

• Description:

  Glyphosate-d2-1 is the deuterium labeled Glyphosate[1]. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants[2].

• UNSPSC:

  12352211

• Target:

  Apoptosis; Autophagy; Isotope-Labeled Compounds; Necroptosis

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Apoptosis; Autophagy; Others

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Purity:

  99.89

• Solubility:

  H2O : 13.89 mg/mL (ultrasonic; warming)

• Smiles:

  OC(C([2H])([2H])NCP(O)(O)=O)=O

• Molecular Formula:

  C3H6D2NO5P

• Molecular Weight:

  171.09

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Greim H, et al. Evaluation of carcinogenic potential of the herbicide glyphosate, drawing on tumor incidence data from fourteen chronic/carcinogenicity rodent studies. Crit Rev Toxicol. 2015;45 (3) :185-208.|[3]Zhang JW, et al The toxic effects and possible mechanisms of glyphosate on mouse oocytes. Chemosphere. 2019 Dec237:124435.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported