Dinotefuran-d3

CAT: 0804-HY-B0827SSize: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0827SSize:1 mg
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Description
Dinotefuran-d3 is the deuterium labeled Dinotefuran[1]. Dinotefuran is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors[2].
CAS Number
[2934813-27-9]
Product Name Alternative
MTI-446-d3
UNSPSC
12352005
Hazard Statement
H332, H410
Target
NAChR; Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cardiovascular Disease
Purity
98.71
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])N/C(N[N+]([O-])=O)=N\CC1CCOC1
Molecular Formula
C7H11D3N4O3
Molecular Weight
205.23
Precautions
H332, H410
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Liu T, et al. Biochemical and genetic toxicity of dinotefuran on earthworms (Eisenia fetida) . Chemosphere. 2017 Jun;176:156-164.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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