Products for Research Use Only

Pentoxifylline (Standard)

CAT: 0804-HY-B0715R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0715R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pentoxifylline (Standard) is the analytical standard of Pentoxifylline. This product is intended for research and analytical applications. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].
CAS Number
6493-05-6
Product Name Alternative
BL-191 (Standard) ; PTX (Standard) ; Oxpentifylline (Standard)
UNSPSC
12352005
Hazard Statement
H302-H312-H332-H336
Target
Autophagy; HIV; Phosphodiesterase (PDE) ; Reference Standards
Type
Reference compound
Related Pathways
Anti-infection; Autophagy; Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/pentoxifylline-standard.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCCCC(C)=O)N(C)C2=C(N(C)C=N2)C1=O
Molecular Formula
C13H18N4O3
Molecular Weight
278.31
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Iffat Hassan, et al. Pentoxifylline and its applications in dermatology. Indian Dermatol Online J. 2014 Oct-Dec; 5 (4) : 510–516.|[2]A Ward, et al. Pentoxifylline. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy. Drugs. 1987 Jul;34 (1) :50-97.|[3]Yessica Cristina Castellanos-Esparza, et al. Synergistic promoting effects of pentoxifylline and simvastatin on the apoptosis of triple-negative MDA-MB-231 breast cancer cells. Int J Oncol. 2018 Apr;52 (4) :1246-1254.|[4]Shabnam Movassaghi, et al. Effect of Pentoxifylline on Ischemia- induced Brain Damage and Spatial Memory Impairment in Rat. Iran J Basic Med Sci. 2012 Sep-Oct; 15 (5) : 1083-1090.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
Launched