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Butylphthalide-d3

CAT: 0804-HY-B0647S1Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0647S1Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Butylphthalide-d3 is the deuterium labeled Butylphthalide. Butylphthalide (3-n-Butylphthalide), an anti-cerebral-ischemia agent, is first isolated from the seeds of celery and showes efficacy in animal models of stroke.
Product Name Alternative
3-n-Butylphthalide-d3; 3-Butylphthalide-d3
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Neurological Disease
Purity
99.81
Solubility
10 mM in DMSO
Smiles
O=C1OC(CCCC([2H])([2H])[2H])C2=C1C=CC=C2
Molecular Formula
C12H11D3O2
Molecular Weight
193.26
Precautions
H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Cui LY, et al. Ninety-day administration of dl-3-n-butylphthalide for acute ischemic stroke: a randomized, double-blind trial. Chin Med J (Engl) . 2013;126 (18) :3405-10.|[3]Zhao W, et al. 3-N-butylphthalide improves neuronal morphology after chronic cerebral ischemia. Neural Regen Res. 2014 Apr 1;9 (7) :719-26.|[4]Wang X, et al. Design, synthesis and biological evaluation of hydrogen sulfide releasing derivatives of 3-n-butylphthalide as potential antiplatelet and antithrombotic agents. Org Biomol Chem. 2014 Aug 21;12 (31) :5995-6004.|[5]Wang F, et al. Improvement of cognitive deficits in SAMP8 mice by 3-n-butylphthalide. Neurol Res. 2014 Mar;36 (3) :224-33.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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