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Triclabendazole-d3

CAT: 0804-HY-B0621SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0621SSize:1 mg
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Description
Triclabendazole-d3 is the deuterium labeled Triclabendazole. Triclabendazole is an orally active parasite inhibitor. Triclabendazole has anti-Leishmania activity and induces gasdermin E (GSDME) -dependent pyroptosis by caspase-3 activation. Triclabendazole can be used for the research of fasciola hepatica[1][2][3].
CAS Number
1353867-93-2
Product Name Alternative
CGA89317-d3
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Microtubule/Tubulin; Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Cytoskeleton; Others
Field of Research
Others
Solubility
10 mM in DMSO
Smiles
ClC1=C(C=C(NC(SC([2H])([2H])[2H])=N2)C2=C1)OC(C=CC=C3Cl)=C3Cl
Molecular Formula
C14H6D3Cl3N2OS
Molecular Weight
362.68
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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