Ribavirin-13C5

• Description:

  Ribavirin-13C5 is the 13C-labeled Ribavirin. Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV.

• Product Name Alternative:

  Ribasphere-13C5

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Antibiotic; HCV; Isotope-Labeled Compounds; RSV

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection; Others

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/ribavirin-13c5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[13C@@H]1[13C@H](O)[13C@@H]([13CH2]O)O[13C@H]1N2N=C(C(N)=O)N=C2

• Molecular Formula:

  C3 13C5H12N4O5

• Molecular Weight:

  249.17

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Chang J, et al. Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo. Antiviral Res. 2011 Jan;89 (1) :26-34|[3]Abdel-Hamid NM, et al. Synergistic Effects of Jerusalem Artichoke in Combination with Pegylated Interferon Alfa-2a and Ribavirin Against Hepatic Fibrosis in Rats. Asian Pac J Cancer Prev. 2016;17 (4) :1979-85.|[4]Refaat B, et al. The effects of pegylated interferon-α and ribavirin on liver and serum concentrations of activin-A and follistatin in normal Wistar rat: a preliminary report. BMC Res Notes. 2015 Jun 26;8:265|[5]Savic D, et al. Ribavirin shows immunomodulatory effects on activated microglia. Immunopharmacol Immunotoxicol. 2014 Dec;36 (6) :433-41

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  [1646818-35-0]