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Ribavirin-15N, d2

CAT: 0804-HY-B0434S1Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0434S1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ribavirin-15N, d2 is 15N and deuterated labeled Ribavirin. Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV. Ribavirin also has anti-orthopoxvirus and anti-variola activities.
Product Name Alternative
ICN-1229-15N, d2
UNSPSC
12352005
Target
Antibiotic; HCV; Isotope-Labeled Compounds; Orthopoxvirus; RSV
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@H](O)[C@H](N2N=C(C([15NH2])=O)N=C2)O[C@@H]1C([2H])([2H])O
Molecular Formula
C8H10D2N3 15NO5
Molecular Weight
247.21
References & Citations
[1]Savic D, et al. Ribavirin shows immunomodulatory effects on activated microglia. Immunopharmacol Immunotoxicol. 2014 Dec;36 (6) :433-41|[2]Robert O Baker, et al. Potential antiviral therapeutics for smallpox, monkeypox and other orthopoxvirus infections. Antiviral Res. 2003 Jan;57 (1-2) :13-23.|[3]Refaat B, et al. The effects of pegylated interferon-α and ribavirin on liver and serum concentrations of activin-A and follistatin in normal Wistar rat: a preliminary report. BMC Res Notes. 2015 Jun 26;8:265|[4]Chang J, et al. Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo. Antiviral Res. 2011 Jan;89 (1) :26-34|[5]Abdel-Hamid NM, et al. Synergistic Effects of Jerusalem Artichoke in Combination with Pegylated Interferon Alfa-2a and Ribavirin Against Hepatic Fibrosis in Rats. Asian Pac J Cancer Prev. 2016;17 (4) :1979-85.|[6]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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