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Argatroban-d3

CAT: 0804-HY-B0375SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0375SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Argatroban-d3 is the deuterium labeled Argatroban. Argatroban (MD-805) is a direct, selective thrombin inhibitor.
CAS Number
1356847-56-7
Product Name Alternative
MD-805-d3; MCI-9038-d3
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Thrombin
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@H](C[C@@H](CC1)C)C(O)=O)[C@H](CCCNC(N)=N)NS(=O)(C2=C3C(CC(CN3)C([2H])([2H])[2H])=CC=C2)=O
Molecular Formula
C23H33D3N6O5S
Molecular Weight
511.65
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Kawada, T., et al., Argatroban, an attractive anticoagulant, for left heart bypass with centrifugal pump for repair of traumatic aortic rupture. Jpn J Thorac Cardiovasc Surg, 1999. 47 (3) : p. 104-9.|[3]Jang, I.K., et al., A multicenter, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (TPA) in acute myocardial infarction: myocardial infarction with novastan and TPA (MINT) study. J Am Coll Cardiol, 1999. 33 (7) : p. 1879-85.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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