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Propylthiouracil-d5

CAT: 0804-HY-B0346SSize: 2.5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0346SSize:2.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Propylthiouracil-d5 is the deuterium labeled Propylthiouracil. Propylthiouracil (6-Propyl-2-thiouracil) is a thyroperoxidase and 5'-deiodinase inhibitor.
CAS Number
1189423-94-6
Product Name Alternative
6-n-Propylthiouracil-d5; 6-Propyl-2-thiouracil-d5; PTU-d5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Endocrinology
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])C([2H])([2H])CC1=CC(NC(N1)=S)=O
Molecular Formula
C7H5D5N2OS
Molecular Weight
175.26
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Nakamura, H., et al., Comparison of methimazole and propylthiouracil in patients with hyperthyroidism caused by Graves' disease. J Clin Endocrinol Metab, 2007. 92 (6) : p. 2157-62.|[3]Taurog, A. and M.L. Dorris, A reexamination of the proposed inactivation of thyroid peroxidase in the rat thyroid by propylthiouracil. Endocrinology, 1989. 124 (6) : p. 3038-42.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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