Propylthiouracil-d5
CAT:
804-HY-B0346S
Size:
2.5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Propylthiouracil-d5
- CAS Number: 1189423-94-6
- UNSPSC Description: Propylthiouracil-d5 is the deuterium labeled Propylthiouracil. Propylthiouracil (6-Propyl-2-thiouracil) is a thyroperoxidase and 5'-deiodinase inhibitor.
- Target Antigen: Isotope-Labeled Compounds
- Type: Isotope-Labeled Compounds
- Related Pathways: Others
- Field of Research: Endocrinology
- Solubility: 10 mM in DMSO
- Smiles: [2H]C([2H])([2H])C([2H])([2H])CC1=CC(NC(N1)=S)=O
- Molecular Weight: 175.26
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Nakamura, H., et al., Comparison of methimazole and propylthiouracil in patients with hyperthyroidism caused by Graves' disease. J Clin Endocrinol Metab, 2007. 92(6): p. 2157-62.|[3]Taurog, A. and M.L. Dorris, A reexamination of the proposed inactivation of thyroid peroxidase in the rat thyroid by propylthiouracil. Endocrinology, 1989. 124(6): p. 3038-42.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported