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Dapoxetine-d6

CAT: 0804-HY-B0304SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0304SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dapoxetine-d6 is the deuterium labeled Dapoxetine[1]. Dapoxetine (LY-210448) is an orally active and selective serotonin reuptake inhibitor (SSRI) . Dapoxetine can be used for the research of premature ejaculation (PE) [2].
CAS Number
1132642-58-0
UNSPSC
12352005
Target
Serotonin Transporter
Type
Isotope-Labeled Compounds
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])N(C([2H])([2H])[2H])[C@H](C1=CC=CC=C1)CCOC2=CC=CC3=C2C=CC=C3
Molecular Formula
C21H17D6NO
Molecular Weight
311.45
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Muammer Kendirci, et al. Dapoxetine, a novel selective serotonin transport inhibitor for the treatment of premature ejaculation. Ther Clin Risk Manag. 2007 Jun;3 (2) :277-89.|[3]Rabab H Sayed, et al. Dapoxetine attenuates testosterone-induced prostatic hyperplasia in rats by the regulation of inflammatory and apoptotic proteins. Toxicol Appl Pharmacol. 2016 Nov 15;311:52-60.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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