Dapoxetine

• Description :

  Dapoxetine (LY-210448) is an orally active and selective serotonin reuptake inhibitor (SSRI) . Dapoxetine can be used for the research of premature ejaculation (PE) [1].

• Product Name Alternative :

  (S) - (+) -Dapoxetine; LY-210448

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Serotonin Transporter

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/dapoxetine.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CN(C)[C@H](C1=CC=CC=C1)CCOC2=CC=CC3=C2C=CC=C3

• Molecular Formula :

  C21H23NO

• Molecular Weight :

  305.41

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

• References & Citations :

  [1]Muammer Kendirci, et al. Dapoxetine, a novel selective serotonin transport inhibitor for the treatment of premature ejaculation. Ther Clin Risk Manag. 2007 Jun;3 (2) :277-89.|[2]Rabab H Sayed, et al. Dapoxetine attenuates testosterone-induced prostatic hyperplasia in rats by the regulation of inflammatory and apoptotic proteins. Toxicol Appl Pharmacol. 2016 Nov 15;311:52-60.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [119356-77-3]