Ethionamide-d3

• Description:

  Ethionamide-d3 is the deuterium labeled Ethionamide. Ethionamide (2-ethylthioisonicotinamide) is an antibiotic used in the treatment of tuberculosis.

• Product Name Alternative:

  2-ethylthioisonicotinamide-d3

• UNSPSC:

  12352005

• Target:

  Antibiotic; Bacterial; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection; Others

• Field of Research:

  Infection

• Solubility:

  10 mM in DMSO

• Smiles:

  NC(C1=CC=NC(CC([2H])([2H])[2H])=C1)=S

• Molecular Formula:

  C8H7D3N2S

• Molecular Weight:

  169.26

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Vannelli, T.A., A. Dykman, and P.R. Ortiz de Montellano, The antituberculosis drug ethionamide is activated by a flavoprotein monooxygenase. J Biol Chem, 2002. 277 (15) : p. 12824-9.|[3]Quemard, A., G. Laneelle, and C. Lacave, Mycolic acid synthesis: a target for ethionamide in mycobacteria? Antimicrob Agents Chemother, 1992. 36 (6) : p. 1316-21.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported