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(R) -Oxybutynin

CAT: 0804-HY-B0267CSize: 1 EachDry Ice: NoHazardous: No
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Description
(R) -Oxybutynin (Aroxybutynin) is the racemic isomer of Oxybutynin and an orally active muscarinic receptor antagonist. (R) -Oxybutynin has antispasmodic, antimuscarinic, and anticholinergic activities and competitively antagonizes carbachol-induced contractions. (R) -Oxybutynin can be used to study urinary incontinence caused by neurogenic bladder dysfunction[1][2][3].
CAS Number
119618-21-2
Product Name Alternative
Aroxybutynin
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/r-oxybutynin.html
Solubility
10 mM in DMSO
Smiles
CCN(CC)CC#CCOC([C@@](C1CCCCC1)(C2=CC=CC=C2)O)=O
Molecular Formula
C22H31NO3
Molecular Weight
357.49
References & Citations
[1]Smith ER, et al. Comparison of the antimuscarinic and antispasmodic actions of racemic oxybutynin and desethyloxybutynin and their enantiomers with those of racemic terodiline. Arzneimittelforschung. 1998 Oct;48 (10) :1012-8.|[2]Zobrist RH, et al. Pharmacokinetics of the R- and S-enantiomers of oxybutynin and N-desethyloxybutynin following oral and transdermal administration of the racemate in healthy volunteers. Pharm Res. 2001 Jul;18 (7) :1029-34.|[3]Siddiqui MA, et al. Oxybutynin extended-release: a review of its use in the management of overactive bladder. Drugs. 2004;64 (8) :885-912.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3

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