Oxybutynin-d11 (chloride)

Oxybutynin-d11 (chloride)

• CAS Number: 1185151-95-4
• UNSPSC Description: Oxybutynin-d11 (chloride) is the deuterium labeled Oxybutynin chloride. Oxybutynin chloride is an anticholinergic agent, which inhibits vascular Kv channels in a concentration-dependent manner, with an IC50 of 11.51 μM[1].
• Target Antigen: Isotope-Labeled Compounds; mAChR; Potassium Channel
• Type: Isotope-Labeled Compounds
• Related Pathways: GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling;Others
• Field of Research: Neurological Disease
• Purity: 97.39
• Solubility: DMSO : 100 mg/mL (ultrasonic;warming)
• Smiles: CCN(CC)CC#CCOC(C(C1([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C1([2H])[2H])(C2=CC=CC=C2)O)=O.Cl
• Molecular Weight: 405.02
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Li H, The anticholinergic drug oxybutynin inhibits voltage-dependent K⁺ channels in coronary arterial smooth muscle cells. Clin Exp Pharmacol Physiol. 2019 Nov;46(11):1030-1036.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported