Cephalexin-d5 (monohydrate)

CAT: 0804-HY-B0200BSSize: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0200BSSize:1 mg
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Description
Cephalexin-d5 (monohydrate) is the deuterium labeled Cephalexin monohydrate. Cephalexin monohydrate is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin monohydrate kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia, ?strep throat, and bacterial endocarditis, et al[1].
Product Name Alternative
Cefalexin hydrate-d5; Cephacillin hydrate-d5
UNSPSC
12352005
Target
Antibiotic; Bacterial; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Field of Research
Infection
Solubility
10 mM in DMSO
Smiles
O=C1N2[C@@](SCC(C)=C2C(O)=O)([H])[C@@H]1NC([C@@H](C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])N)=O.O
Molecular Formula
C16H14D5N3O5S
Molecular Weight
370.43
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Cefalexin|[3]Hongbaek Cho, et al. Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery. Cell. . 2014 Dec 4;159 (6) :1300-11.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
β-lactam

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