Cephalexin-d5 (hydrate)

• Description :

  Cephalexin-d5 (hydrate) is deuterium labeled Cephalexin (monohydrate) . Cephalexin (Cefalexin) monohydrate is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) monohydrate targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al[1][2][3].

• UNSPSC :

  12352005

• Target :

  Antibiotic; Bacterial; Isotope-Labeled Compounds; Penicillin-binding protein (PBP)

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Others

• Field of Research :

  Cancer

• Purity :

  93.70

• Smiles :

  N[C@H](C1=C(C([2H])=C(C([2H])=C1[2H])[2H])[2H])C(N[C@@H]2C(N3C2SCC(C)=C3C(O)=O)=O)=O.O

• Molecular Formula :

  C16H14D5N3O5S

• Molecular Weight :

  370.43

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Cho H, et, al. Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery. Cell. 2014 Dec 4;159 (6) :1300-11. |[3]Buck RE, et, al. Cefadroxil, a new broad-spectrum cephalosporin. Antimicrob Agents Chemother. 1977 Feb;11 (2) :324-30.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported