Mosapride-d5

• Description:

  Mosapride-d5 is the deuterium labeled Mosapride. Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.

• UNSPSC:

  12352005

• Target:

  5-HT Receptor; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling; Others

• Field of Research:

  Neurological Disease

• Solubility:

  10 mM in DMSO

• Smiles:

  FC (C=C1) =CC=C1CN (CCO2) CC2CNC (C3=C (C=C (C (Cl) =C3) N) OC ([2H]) ([2H]) C ([2H]) ([2H]) [2H]) =O

• Molecular Formula:

  C21H20D5ClFN3O3

• Molecular Weight:

  426.92

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Tack J, et al. Systematic review: cardiovascular safety profile of 5-HT (4) agonists developed for gastrointestinal disorders. Aliment Pharmacol Ther. 2012 Apr;35 (7) :745-67.|[3]Curran MP, et al. Mosapride in gastrointestinal disorders. Drugs. 2008;68 (7) :981-91.|[4]Odaka T, et al. Serotonin 5- HT4 receptor agonist (mosapride citrate) . Nihon Rinsho. 2006 Aug;64 (8) :1491-4.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  1246820-66-5