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Aztreonam-d6

CAT: 0804-HY-B0129SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0129SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Aztreonam-d6 is deuterium labeled Aztreonam. Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3) .
CAS Number
1127452-94-1
Product Name Alternative
SQ-26,776-d6
UNSPSC
12352005
Target
Antibiotic; Bacterial; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Purity
99.29
Solubility
10 mM in DMSO
Smiles
OC(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])O/N=C(C1=CSC(N)=N1)\C(N[C@H]2[C@@H](N(C2=O)S(=O)(O)=O)C)=O)=O
Molecular Formula
C13H11D6N5O8S2
Molecular Weight
441.47
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Guay DR, et al. Aztreonam, a new monobactam antimicrobial. Clin Pharm. 1985 Sep-Oct;4 (5) :516-26.|[3]Kobayashi Y, et al. Synergy with aztreonam and arbekacin or tobramycin against Pseudomonas aeruginosa isolated from blood. J Antimicrob Chemother. 1992 Dec;30 (6) :871-2.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
β-lactam