Aztreonam

• Description:

  Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3) .

• Product Name Alternative:

  SQ-26,776

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Antibiotic; Bacterial; Penicillin-binding protein (PBP)

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Aztreonam.html

• Concentration:

  10mM

• Purity:

  99.64

• Solubility:

  DMSO : 50 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic)

• Smiles:

  CC (C) (O/N=C (C1=CSC (N) =N1) \C (N[C@H]2[C@H] (C) N (S (=O) (O) =O) C2=O) =O) C (O) =O

• Molecular Formula:

  C13H17N5O8S2

• Molecular Weight:

  435.43

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Kobayashi Y, et al. Synergy with aztreonam and arbekacin or tobramycin against Pseudomonas aeruginosa isolated from blood. J Antimicrob Chemother. 1992 Dec;30 (6) :871-2.|[2]Guay DR, et al. Aztreonam, a new monobactam antimicrobial. Clin Pharm. 1985 Sep-Oct;4 (5) :516-26.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• Isoform:

  β-lactam

• CAS Number:

  78110-38-0