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Roslin 2 (bromide)

CAT: 0804-HY-A0280Size: 1 mgDry Ice: NoHazardous: No
CAT#: HY-A0280Size: 1 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator with anticancer effects. Roslin 2 bromide binds FAK, disrupts the binding of FAK and p53[1].
CAS Number
[29574-21-8]
Product Name Alternative
Benzylhexamethylenetetramine (bromide)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
FAK; MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/roslin-2-bromide.html
Purity
99.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
[N@@]12C[N+](C[N@](C3)C1)(C[N@@]3C2)CC4=CC=CC=C4.[Br-]
Molecular Formula
C13H19BrN4
Molecular Weight
311.22
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Vita M Golubovskaya, et al. Disruption of focal adhesion kinase and p53 interaction with small molecule compound R2 reactivated p53 and blocked tumor growth. BMC Cancer. 2013 Jul 11;13:342.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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