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L-Pyroglutamic acid (sodium)

CAT: 0804-HY-76082ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-76082ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-Pyroglutamic acid sodium is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid sodium is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid sodium can be used as a biomarker for systemic lupus erythematosus (SLE) [1].
CAS Number
28874-51-3
UNSPSC
12352200
Hazard Statement
H272-H315-H319
Target
Endogenous Metabolite
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/l-pyroglutamic-acid-sodium.html
Solubility
10 mM in DMSO
Smiles
O=C(O[Na])[C@H](CC1)NC1=O
Molecular Formula
C5H6NNaO3
Molecular Weight
151.10
Precautions
P210-P220-P264-P280-P302+P352-P362+P364-P370+P378-P501
References & Citations
[1]Jiménez-Arias D, et al. Lettuce plants treated with L-pyroglutamic acid increase yield under water deficit stress[J]. Environmental and experimental botany, 2019, 158: 215-222.|[2]Zhang Q, et al., Metabolomic profiling reveals serum L-pyroglutamic acid as a potential diagnostic biomarker for systemic lupus erythematosus. Rheumatology (Oxford) . 2021 Feb 1;60 (2) :598-606.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite