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L-Pyroglutamic acid

CAT: 0804-HY-76082-01Size: 25 gDry Ice: NoHazardous: No
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CAT#:0804-HY-76082-01Size:25 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid can be used as a biomarker for systemic lupus erythematosus (SLE) [1].
CAS Number
98-79-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/_S_-5-oxopyrrolidine-2-carboxylic_acid.html
Purity
98.57
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(O)[C@H](CC1)NC1=O
Molecular Formula
C5H7NO3
Molecular Weight
129.11
Precautions
H302, H315, H319, H335
References & Citations
[1]Jiménez-Arias D, et al. Lettuce plants treated with L-pyroglutamic acid increase yield under water deficit stress[J]. Environmental and experimental botany, 2019, 158: 215-222.|[2]Zhang Q, et al., Metabolomic profiling reveals serum L-pyroglutamic acid as a potential diagnostic biomarker for systemic lupus erythematosus. Rheumatology (Oxford) . 2021 Feb 1;60 (2) :598-606.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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