Cinacalcet-d3

CAT: 0804-HY-70037SSize: 10 mgDry Ice: NoHazardous: No
CAT#:0804-HY-70037SSize:10 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Cinacalcet-d3 is the deuterium labeled Cinacalcet. Cinacalcet (AMG 073) is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment.
Product Name Alternative
AMG 073-D3
UNSPSC
12352005
Target
CaSR; Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease
Solubility
10 mM in DMSO
Smiles
FC(F)(C1=CC(CCCN[C@@H](C2=C3C=CC=CC3=CC=C2)C([2H])([2H])[2H])=CC=C1)F
Molecular Formula
C22H19D3F3N
Molecular Weight
360.43
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Colloton M, et al. Cinacalcet HCl attenuates parathyroid hyperplasia in a rat model of secondary hyperparathyroidism. Kidney Int. 2005 Feb;67 (2) :467-76.; D.A. Bushinsky, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69 (9) :1586-92.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-70037-01Cinacalcet
HY-70037A-01Cinacalcet (hydrochloride)
HY-70037RCinacalcet (Standard)
HY-70037AR-01Cinacalcet (hydrochloride) (Standard)
HY-135601Cinacalcet metabolite M4
HY-I0191-01Cinacalcet impurity 5
HY-I0392A-01(S) -Cinacalcet (hydrochloride)
HY-I0434-01Cinacalcet impurity 1
HY-I0648A-01Cinacalcet impurity 50
HY-I0192-01Cinacalcet impurity 9

Alternative Products

CatalogName
ESS0297-01(R) -Cinacalcet-D3
ESS0299-01(S) -Cinacalcet-D3
sc-219810Rac Cinacalcet-d3 Hydrochloride
ESS0298-01(R) -Cinacalcet-D3 Hydrochloride
ESS0559-01Rac-Cinacalcet-D3 Hydrochloride
RM-C030460-01N-Nitroso Cinacalcet-D3
ESS0300-01(S) -Cinacalcet-D3 Hydrochloride
ESS0560-01N-Nitroso Cinacalcet-D3 (mixture of diastereomers)
T8403-01Cinacalcet
TRC-C441800-10MGCinacalcet Hydrochloride

Popular Products