BCN-HS-PEG2-VA-PABC-SG3199

BCN-HS-PEG2-VA-PABC-SG3199

• CAS Number: 2126805-05-6
• UNSPSC Description: BCN-HS-PEG2-VA-PABC-SG3199 (Compound 4) is a pyrrolobenzodiazepine that can be used as a agent linker of antibody-drug conjugates (ADC)[1]. BCN-HS-PEG2-VA-PABC-SG3199 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
• Target Antigen: ADC Linker
• Type: Reference compound
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/bcn-hs-peg2-va-pabc-sg3199.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N([C@H]1O)C(C(C(N2[C@@]1([H])CC(C)=C2)=O)=C3)=CC(OCCCCCOC(C=C(N=C[C@@](C4)([H])N(C=C4C)C5=O)C5=C6)=C6OC)=C3OC)OCC(C=C7)=CC=C7NC([C@H](C)NC([C@H](C(C)C)NC(COCCOCCN[S](NC(OC[C@@H]8[C@@]9([H])[C@]8([H])CCC#CCC9)=O)(=O)=O)=O)=O)=O
• Molecular Weight: 1322.48
• References & Citations: [1]Patricius Hendrikus Cornelis VAN BERKEL. Pyrrolobenzodiazepine-antibody conjugates. Patent WO2018146199A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported