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Dehydro Palonosetron

CAT: 0804-HY-44132Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-44132Size:1 Each
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Description
Dehydro Palonosetron (RS 42358-197) is a potent, seslective and orally active 5-HT3 receptor antagonist. Dehydro Palonosetron has no effect on the activities of 5-HT1 receptors, 5-HT2 receptors or 5-HT4 receptors[1].
CAS Number
135729-56-5
Product Name Alternative
RS 42358-197
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dehydro-palonosetron.html
Solubility
10 mM in DMSO
Smiles
O=C1N([C@@H]2CN3CCC2CC3)C=C4C5=C1C=CC=C5CCC4
Molecular Formula
C19H22N2O
Molecular Weight
294.39
References & Citations
[1]R M Eglen, et al. RS 42358-197, a novel and potent 5-HT3 receptor antagonist, in vitro and in vivo. J Pharmacol Exp Ther. 1993 Aug;266 (2) :535-43.|[2]B Costall, et al. The effect of the 5-HT3 receptor antagonist, RS-42358-197, in animal models of anxiety. Eur J Pharmacol. 1993 Mar 30;234 (1) :91-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Lactoferrin

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