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Methoxsalen-d3

CAT: 0804-HY-30151SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-30151SSize:1 mg
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Description
Methoxsalen-d3 is the deuterium labeled Methoxsalen[1]. Methoxsalen (8-Methoxypsoralen) is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450), is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight[2].
CAS Number
80386-99-8
Product Name Alternative
8-Methoxypsoralen-d3; Xanthotoxin-d3; 8-MOP-d3
UNSPSC
12352005
Hazard Statement
H302, H317, H341, H351
Target
Cytochrome P450
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Inflammation/Immunology
Purity
99.93
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])OC1=C(OC=C2)C2=CC(C=C3)=C1OC3=O
Molecular Formula
C12H5D3O4
Molecular Weight
219.21
Precautions
H302, H317, H341, H351
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Alsharari SD, et al. Pharmacokinetic and Pharmacodynamics Studies of Nicotine After Oral Administration in Mice: Effects of Methoxsalen, a CYP2A5/6 Inhibitor. Nicotine Tob Res. 2014 Jan;16 (1) :18-25.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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