Methoxsalen

• Description:

  Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.

• Product Name Alternative:

  8-Methoxypsoralen; Xanthotoxin; 8-MOP

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H317, H341, H351

• Target:

  Cytochrome P450

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Methoxsalen.html

• Concentration:

  10mM

• Purity:

  99.98

• Solubility:

  DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL

• Smiles:

  O=C1OC(C(C=C1)=C2)=C(OC)C3=C2C=CO3

• Molecular Formula:

  C12H8O4

• Molecular Weight:

  216.19

• Precautions:

  H302, H317, H341, H351

• References & Citations:

  [1]Alsharari SD, et al. Pharmacokinetic and Pharmacodynamics Studies of Nicotine After Oral Administration in Mice: Effects of Methoxsalen, a CYP2A5/6 Inhibitor. Nicotine Tob Res. 2014 Jan;16 (1) :18-25.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  Launched

• CAS Number:

  298-81-7