α-Eleostearic acid

• Description:

  α-Eleostearic acid (cis-Eleostearic acid), a conjugated linolenic acid, is an apoptosis inducer. α-Eleostearic acid is also a ferroptosis inducer. α-Eleostearic acid exhibits antioxidant and antitumor activity[1][2][3].

• Product Name Alternative:

  Cis-Eleostearic acid

• UNSPSC:

  12352211

• Hazard Statement:

  H225, H301+H311+H331, H370

• Target:

  Apoptosis; Ferroptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Cancer; Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/α-eleostearic-acid.html

• Concentration:

  35.92 mM * 100 μL in Methanol

• Purity:

  98.00

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCC/C=C/C=C/C=C\CCCCCCCC (O) =O

• Molecular Formula:

  C18H30O2

• Molecular Weight:

  278.43

• Precautions:

  H225, H301+H311+H331, H370

• References & Citations:

  [1]Kobori M, et, al. Alpha-eleostearic acid and its dihydroxy derivative are major apoptosis-inducing components of bitter gourd. J Agric Food Chem. 2008 Nov 26;56 (22) :10515-20.|[2]Saha SS, et, al. Comparative study of antioxidant activity of alpha-eleostearic acid and punicic acid against oxidative stress generated by sodium arsenite. Food Chem Toxicol. 2009 Oct;47 (10) :2551-6. |[3]Beatty A, et, al. Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1. Nat Commun. 2021 Apr 14;12 (1) :2244.

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  -80°C

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  506-23-0