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Trans-Zeatin-d5

CAT: 0804-HY-19700SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-19700SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Trans-Zeatin-d5 is deuterium labeled trans-Zeatin. trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.
CAS Number
72963-19-0
UNSPSC
12352005
Target
Endogenous Metabolite; ERK; MEK
Type
Isotope-Labeled Compounds
Related Pathways
MAPK/ERK Pathway; Metabolic Enzyme/Protease; Stem Cell/Wnt
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Purity
99.20
Solubility
10 mM in DMSO|DMSO : 25mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC([2H])([2H])/C(C([2H])([2H])[2H])=C/CNC1=C2C(N=CN2)=NC=N1
Molecular Formula
C10H8D5N5O
Molecular Weight
224.27
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Ji C, et al. Trans-Zeatin attenuates ultraviolet induced down-regulation of aquaporin-3 in cultured human skin keratinocytes. Int J Mol Med. 2010 Aug;26 (2) :257-63.|[3]Li Q, et al. Endogenous trans-zeatin content in plants with different metal-accumulating ability: a field survey. Environ Sci Pollut Res Int. 2016 Dec;23 (23) :23422-23435. Epub 2016 Sep 9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported