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SSR-241586

CAT: 0804-HY-19456Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19456Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SSR-241586 is an antagonist of neurokinin receptors. SSR-241586 is shown to be active in the treatment of depression, schizophrenia, urinary trouble, emesis, and irritable bowel syndrome (IBS) [1][2].
CAS Number
1239279-30-1
UNSPSC
12352005
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/ssr-241586.html
Solubility
10 mM in DMSO
Smiles
O=C(C1(N2CCCCC2)CCN(CC[C@@]3(C4=CC=C(Cl)C(Cl)=C4)CN(C(C5=CC=CC=C5)=O)CCO3)CC1)N(C)C
Molecular Formula
C32H42Cl2N4O3
Molecular Weight
601.61
References & Citations
[1]Métro TX, et al. Asymmetric synthesis of an antagonist of neurokinin receptors: SSR 241586. J Org Chem. 2011 Apr 15;76 (8) :2594-602.|[2]Cochi A, et al. Enantioselective synthesis of SSR 241586 by using an organo-catalyzed Henry reaction. Org Lett. 2010 Aug 20;12 (16) :3693-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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