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Nedocromil sodium

CAT: 0804-HY-16344Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-16344Size:1 Each
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Description
Nedocromil sodium suppresses the action or formation of multiple mediators, including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2) .
CAS Number
69049-74-7
Product Name Alternative
FPL 59002KP; Nedocromil disodium salt
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Histamine Receptor; Leukotriene Receptor; Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/NEDOCROMIL_SODIUM.html
Solubility
DMSO : 5.2 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(C2=CC3=C(N(CC)C(C([O-])=O)=CC3=O)C(CCC)=C2O1)=O)[O-].[Na+].[Na+]
Molecular Formula
C19H15NNa2O7
Molecular Weight
415.30
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Wells E, et al. Characterization of primate bronchoalveolar mast cells. II. Inhibition of histamine, LTC4, and PGD2 release from primate bronchoalveolar mast cells and a comparison with rat peritoneal mastcells. J Immunol. 1986 Dec 15;137 (12) :3941-5.|[2]Myocardial remodeling in diabetic cardiomyopathy associated with cardiac mast cell activation. Huang ZG, et al. PLoS One. 2013;8 (3) :e60827.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
DP; LTC4/CysLT2

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