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Nedocromil

CAT: 0804-HY-13448-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13448-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nedocromil suppresses the action or formation of multiple mediators, including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2) .
CAS Number
69049-73-6
Product Name Alternative
FPL 59002
UNSPSC
12352005
Hazard Statement
H319
Target
Histamine Receptor; Leukotriene Receptor; Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Nedocromil.html
Concentration
10mM
Purity
98.75
Solubility
DMSO : 16.67 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(C2=CC3=C(N(CC)C(C(O)=O)=CC3=O)C(CCC)=C2O1)=O)O
Molecular Formula
C19H17NO7
Molecular Weight
371.34
Precautions
H319
References & Citations
[1]Wells E, et al. Characterization of primate bronchoalveolar mast cells. II. Inhibition of histamine, LTC4, and PGD2 release from primate bronchoalveolar mast cells and a comparison with rat peritoneal mastcells. J Immunol. 1986 Dec 15;137 (12) :3941-5.|[2]Myocardial remodeling in diabetic cardiomyopathy associated with cardiac mast cell activation. Huang ZG, et al. PLoS One. 2013;8 (3) :e60827.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
DP; LTC4/CysLT2