HSGN-218

• Description :

  HSGN-218 is an antibacterial agent with low Caco-2 permeability. HSGN-218 efficiently inhibits the growth of different C. difficile species with MIC values ranging from 0.007 μM to 0.07 μM.[1]

• UNSPSC :

  12352005

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/hsgn-218.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NC1=NN=C(C2=CC(Cl)=CC(Cl)=C2)O1)C3=CC=C(SC(F)(F)F)C=C3

• Molecular Formula :

  C16H8Cl2F3N3O2S

• Molecular Weight :

  434.22

• References & Citations :

  [1]Naclerio GA, et al. Ultrapotent Inhibitor of Clostridioides difficile Growth, Which Suppresses Recurrence In Vivo. J Med Chem. 2020 Oct 22;63 (20) :11934-11944.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2519410-44-5]