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FABP4-IN-3

CAT: 0804-HY-163032-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-163032-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FABP4-IN-3 (compound C3) is a highly selective FABP4 inhibitor (FABP4 Ki = 25 ± 3a nM, FABP3 Ki = 15.03 μM) which exhibits a 601-fold selectivity over FABP3. FABP4-IN-3 also shows metabolic stability and potent cellular anti-inflammatory activity, making it promising to get involved in the research of metabolic disease, cardiac dysfunction and inflammation-related disease[1].
UNSPSC
12352005
Target
FABP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/fabp4-in-3.html
Purity
99.64
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC=CC(NC2=CC=CC(Cl)=C2C3=CC=CC=C3)=C1C(O)=O
Molecular Formula
C20H16ClNO2
Molecular Weight
337.80
References & Citations
[1]Yechun Xu, et al. Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3. European Journal of Medicinal Chemistry. 2023, Journal Pre-proof.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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