PRL-IN-1

PRL-IN-1

• CAS Number: 331431-75-5
• UNSPSC Description: PRL-IN-1 (compound 43) is a phosphatase of regenerating liver (PRL) inhibitor that directly binds the PRL1 trimer interface and obstructs PRL1 trimerization. PRL-IN-1 shows potent anticancer activities[1].
• Target Antigen: Phosphatase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/prl-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N/N=C\C1=CC=C(C(O)=O)C=C1)C2=CC=CC(N3CC(C=C(C)C(C)=C4)=C4C3)=C2
• Molecular Weight: 413.47
• References & Citations: [1]Yunpeng Bai, et al. Novel Anticancer Agents Based on Targeting the Trimer Interface of the PRL Phosphatase. Cancer Res. 2016 Aug 15;76(16):4805-15.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported