PRL-IN-1

• UNSPSC Description:

  PRL-IN-1 (compound 43) is a phosphatase of regenerating liver (PRL) inhibitor that directly binds the PRL1 trimer interface and obstructs PRL1 trimerization. PRL-IN-1 shows potent anticancer activities[1].

• Target Antigen:

  Phosphatase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/prl-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N/N=C\C1=CC=C(C(O)=O)C=C1)C2=CC=CC(N3CC(C=C(C)C(C)=C4)=C4C3)=C2

• Molecular Weight:

  413.47

• References & Citations:

  [1]Yunpeng Bai, et al. Novel Anticancer Agents Based on Targeting the Trimer Interface of the PRL Phosphatase. Cancer Res. 2016 Aug 15;76(16):4805-15.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  331431-75-5