PRL 3195

CAT: 0804-HY-P4469Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P4469Size:1 Each
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Description
PRL 3195 is a somatostatin receptor antagonist with Kis of 6, 17, 66, 1000 and 1000 nM for human somatostatin receptors (sst5, sst2, sst3, sst1 and sst4, respectively) [1].
CAS Number
[341519-04-8]
UNSPSC
12352209
Target
Somatostatin Receptor; Urotensin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/prl-3195.html
Solubility
H2O
Smiles
O=C([C@@H](NC([C@@H](CSSC[C@H](NC([C@](NC([C@@H](N(C1=O)C)CCCCN)=O)([H])[C@H](O)C)=O)C(N[C@H](C(N)=O)CC2=CC3=C(C=CC=C3)C=C2)=O)NC([C@@H](N)CC4=CC=C(C=C4)Cl)=O)=O)CC5=CN=CC=C5)N[C@@H]1CC6=CNC7=CC=CC=C67
Molecular Formula
C58H69ClN12O9S2
Molecular Weight
1177.83
References & Citations
[1]Rossowski WJ, et al. Human urotensin II-induced aorta ring contractions are mediated by protein kinase C, tyrosine kinases and Rho-kinase: inhibition by somatostatin receptor antagonists. Eur J Pharmacol. 2002 Mar 8;438 (3) :159-70.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
SSTR1; SSTR2; SSTR3; SSTR4; SSTR5

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