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LBG30300

CAT: 0804-HY-162117Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162117Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LBG30300 is a subtype-selective mGlu2 receptor agonist EC50 0.6 nM. LBG30300 is blood-brain barrier permeable[1].
UNSPSC
12352211
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lbg30300.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H]1[C@@H]([C@H](N)C(O)=O)[C@@H]1CC(O)=O)O
Molecular Formula
C8H11NO6
Molecular Weight
217.18
References & Citations
[1]Liu N, et al. Design, Synthesis, Pharmacology, and In Silico Studies of (1S,2S,3S) -2- ((S) -Amino (carboxy) methyl) -3- (carboxymethyl) cyclopropane-1-carboxylic Acid (LBG30300) : A Picomolar Potency Subtype-Selective mGlu2 Receptor Agonist. J Med Chem. 2024 Jan 3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR2; mGluR3; mGluR4; mGluR6; mGluR8

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