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OX04529

CAT: 0804-HY-161107Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161107Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
OX04529 (compound 69) is a potent, selective and orally active agonist of GPR84. OX04529 inhibits FSK-induced cAMP production with an EC50 of 0.0185 nM. OX04529 displayed excellent potency, high G-protein signaling bias[1].
UNSPSC
12352005
Target
GPR84
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ox04529.html
Solubility
10 mM in DMSO
Smiles
[O-][N+]1=CC(CCCC2=CC=C(C(C(F)(F)F)=C2)Cl)=CC(O)=C1
Molecular Formula
C15H13ClF3NO2
Molecular Weight
331.72
References & Citations
[1]Wang P, et al. Development of Highly Potent, G-Protein Pathway Biased, Selective, and Orally Bioavailable GPR84 Agonists. J Med Chem. 2024 Jan 11;67 (1) :110-137.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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