PDH E1-IN-1

CAT: 0804-HY-161048Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-161048Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

PDH E1-IN-1 (compound 24) is a selective TPP-competitive PDH E1 with an IC50 value of 0.99 μM[1].

UNSPSC

12352005

Target

PDHK

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pdh-e1-in-1.html

Solubility

10 mM in DMSO

Smiles

CC1=NC=C(C(N)=N1)CC2=CSC(CCNC3(C4=CC=C(C=C4)OC)COC3)=C2C

Molecular Formula

C23H28N4O2S

Molecular Weight

424.56

References & Citations

[1]Alex H Y Chan, et al. Thiamine analogues featuring amino-oxetanes as potent and selective inhibitors of pyruvate dehydrogenase. Bioorg Med Chem Lett. 2023.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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Catalog	Name
T208797-01	PDH E1-IN-1
60B396	E1
301337	Cyclin E1 (Cyclin-E1)
301337-FITC	Cyclin E1 (Cyclin-E1) (FITC)
301337-HRP	Cyclin E1 (Cyclin-E1) (HRP)
301337-Biotin	Cyclin E1 (Cyclin-E1) (Biotin)
MBS1056834-01	Recombinant Replication protein E1 (E1)
301337-PE	Cyclin E1 (Cyclin-E1) (PE)
301337-APC	Cyclin E1 (Cyclin-E1) (APC)
MBS6452180-01	Cyclin E1 (Cyclin-E1) (AP)

PDH E1-IN-1

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