FAK/aurora kinase-IN-1

FAK/aurora kinase-IN-1

• CAS Number: 2178117-69-4
• UNSPSC Description: FAK/aurora kinase-IN-1 is a FAK and aurora kinase inhibitor with IC50 values of 6.61 nM and 0.91 nM, respectively. FAK/aurora kinase-IN-1 shows anticancer effects (WO2018019252A1; compound 11)[1].
• Target Antigen: Aurora Kinase; FAK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics;Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/fak-aurora-kinase-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: ClC1=C(NC2=C(C(C(N(C)C)=O)=O)C=CC=C2)N=C(N=C1)NC3=CN=C(C=C3)N4CCOCC4
• Molecular Weight: 481.93
• References & Citations: [1]Wenlai Zhou, et al. Novel fused pyridine derivatives useful as fak/aurora kinase inhibitors. WO2018019252A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported