QL47B

CAT: 0804-HY-160246Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-160246Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
QL47B, a biotinylated analogue of QL47 (HY-80003), is a potent inhibitor of BTK, with an IC50 value of 1.3 μM. QL47B has anti-tumor activity[1].
CAS Number
[1579278-92-4]
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ql47b.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=C(C=C1)C=NC3=CC=C(C4=CN(C)N=C4)C=C32)C5=CC=C6C(N(C(/C=C/CNCCOCCOCCOCCNC(CCCC[C@H]7[C@](NC(N8)=O)([H])[C@]8([H])CS7)=O)=O)CC6)=C5
Molecular Formula
C46H55N9O7S
Molecular Weight
878.05
References & Citations
[1]Hong Wu, et al. Discovery of a Potent, Covalent BTK Inhibitor for B‑Cell Lymphoma. ACS Chem Biol. 2014 May 16;9 (5) :1086-91.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-160245-01QL47R
HY-80003-01QL47

Alternative Products

CatalogName
MF-0121243-01QL47B
MF-0117200-01QL47B TFA

Popular Products