QL47R

CAT: 0804-HY-160245-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-160245-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
QL47R is an approximately isosteric analogue of QL47 (HY-80003) . QL47R dose not inhibit the biochemical kinase activity of BTK at concentrations below 10 μM. QL47R dose not display antiproliferative activity on B-Cell Lymphoma Cell Lines at concentrations of less than 10 μM[1].
CAS Number
[1579278-89-9]
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ql47r.html
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=CC2=CN=C3C=CC(C4=CN(C)N=C4)=CC3=C2N1C5=CC=C6C(N(CC6)C(CC)=O)=C5
Molecular Formula
C27H23N5O2
Molecular Weight
449.50
References & Citations
[1]Wu H, et al. Discovery of a potent, covalent BTK inhibitor for B-cell lymphoma. ACS Chem Biol. 2014 May 16;9 (5) :1086-91.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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