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Birelentinib

CAT: 0804-HY-160167Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-160167Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Birelentinib (compound cpd15) is an inhibitor of Bruton's tyrosine kinase (BTK) and mutant BTK with IC50 values of 6.72 and 6.11 nM, respectively[1].
CAS Number
2662512-15-2
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/btk-in-30.html
Solubility
10 mM in DMSO
Smiles
NC1=NC=NN2C([C@@H]3CC[C@H](OC3)CO)=NC(C4=CC=C(C=C4)OC5=C(C(F)=CC=C5)F)=C12
Molecular Formula
C23H21F2N5O3
Molecular Weight
453.44
References & Citations
[1]Quan Zhou, et al. Btk inhibitors. WO2021136219A1. 2020.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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