DL-dithiothreitol-d10

CAT: 0804-HY-15917S-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-15917S-01Size:5 mg
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Description
DL-dithiothreitol-d10 is the deuterated form of DL-dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond[1][2].
CAS Number
[302912-05-6]
Product Name Alternative
DTT-d10
UNSPSC
12352100
Hazard Statement
H302, H315, H319, H335
Target
Disulfidptosis; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Cancer
Purity
98.4
Solubility
10 mM in DMSO
Smiles
[2H]SC([2H])([2H])C(O[2H])([2H])C(O[2H])([2H])C([2H])([2H])S[2H]
Molecular Formula
C4D10O2S2
Molecular Weight
164.31
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Yao H, et al. Establishment of disulfidptosis-related LncRNA signature as biomarkers in colon adenocarcinoma[J]. Cancer Cell International, 2024, 24 (1) : 183.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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