2′-O-Methyl-5′-O-phosphonoadenylyl-(3′→5′)-guanosine (TEA)

CAT:

804-HY-157504

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CAS Number: 2638447-50-2
UNSPSC Description: 2’-O-Methyl-5’-O-phosphonoadenylyl-(3’→5’)-guanosine (TEA) is a trinucleotide cap analogue that regulates protein expression in living cells[1].
Target Antigen: Others
Type: Reference compound
Related Pathways: Others
Field of Research: Others
Assay Protocol: https://www.medchemexpress.com/2-o-methyl-5-o-phosphonoadenylyl-3-5-guanosine-tea.html
Solubility: 10 mM in DMSO
Smiles: O=P(O)(O)OC[C@@H]1[C@@H](OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C4=C(C(N=C(N4)N)=O)N=C3)O2)(O)=O)[C@@H](OC)[C@H](N5C6=NC=NC(N)=C6N=C5)O1.CCN(CC)CC.CCN(CC)CC.CCN(CC)CC
Molecular Weight: 1010.02
References & Citations: [1]Sikorski PJ, et al. The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5' cap modulates protein expression in living cells. Nucleic Acids Res. 2020 Feb 28;48(4):1607-1626.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-157504	2′-O-Methyl-5′-O-phosphonoadenylyl-(3′→5′)-guanosine (TEA)
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