PppApA (sodium)

• Description :

  PppApA sodium is a linear dinucleotide intermediate in the enzymatic production of the bacterial signalling nucleotide c-diAMP. pppApA sodium is formed by conjugation between two molecules of ATP[1].

• UNSPSC :

  12352005

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/pppapa-sodium.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O[C@H]1[C@@H](O[C@@H]([C@H]1OP(OC[C@H]2O[C@@H](N3C4=NC=NC(N)=C4N=C3)[C@@H]([C@@H]2O)O)(O)=O)COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O)=O)N5C6=NC=NC(N)=C6N=C5

• Molecular Formula :

  C20H26N10Na2O19P4

• Molecular Weight :

  880.35

• References & Citations :

  [1]Kasi Manikandan, et al. Two-step synthesis and hydrolysis of cyclic di-AMP in Mycobacterium tuberculosis. PLoS One. 2014 Jan 23;9 (1) :e86096.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported