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AA10

CAT: 0804-HY-157254Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157254Size:1 Each
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Description
AA10 is a potent and irreversible transglutaminase 2 (TG2) inhibitor for cancer research[1].
CAS Number
2134106-02-6
UNSPSC
12352005
Target
Glutaminase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aa10.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC1=CC=CC=C1)N[C@H](C(N2CCN(C(C3=CC=C4C=CC=CC4=C3)=O)CC2)=O)CCCCNC(C=C)=O
Molecular Formula
C32H36N4O5
Molecular Weight
556.65
References & Citations
[1]Akbar A, et al. Structure-Activity Relationships of Potent, Targeted Covalent Inhibitors That Abolish Both the Transamidation and GTP Binding Activities of Human Tissue Transglutaminase. J Med Chem. 2017 Sep 28;60 (18) :7910-7927.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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